Jintropin® is produced by GenScis patented E.coli secretion expression technology. Jintropin® has the same amino acid
sequence with 191 residues as the native human growth hormone produced in the human body. Jintropin® is a highly
purified preparation of hGH protein.
Human Growth Hormone, hGH (rDNA origin) comes in a white lyophilized powder. JINTROPIN stimulates linear growth and increases growth rate in children who lack adequate endogenous growth hormone. In adults with growth hormone deficiency, JINTROPIN reduces fat mass, increases, muscle mass and improves energy, vitality and subjective well-being. In patients suffering from severe burns, AIDS associated muscle wasting, or undergoing major operations, JINTROPIN promotes wound healing, attenuates the protein-catabolic response and improves whole-body nitrogen condition after operation. Jintropin promotes wound healing and attenuate catabolic responses in severe burns, sepsis, multiple trauma, major operations, acute pancreatitis and intestinal fistula. Topical application to promote wound healing in acute wound or chronic ulcer, such as burns, diabetic foot ulcer, chronic venous ulcer and decubital ulcer.
* The 1st rhGH on the Chinese market, launched in 1998
* The largest production capability and best quality in Asia
* Dominant brand of rhGH in China with 70% of market share
* Unique production technology with an E.coli secretion expression system
* The only 191-aa hGH made by secretion technology patented in China
* Proven safety and efficacy for more than 12 years, over 25,000 patients trated in China
* Internal quality control standard higher than that of the national
* The 1st approval in the world to treat burns
* The 1st in the world to develop topical formulation, oral formulation and long-acting formulation
GeneScience Pharmaceuticals Co., Ltd.
Was established in 1996 and is one of the largest and best-equipped biopharmaceutical productions in China. As one of the leading genetic engineering pharmaceutical companies in China, we are the largest manufacturer of recombinant Human Growth Hormone, brandname Jintropin in Asia.
Is produced by patented E.coli secretion expression technolog. Jintropin has the same amino acid sequence with 191 residues as the native human growth hormone produced by the human body. Jintropin is the first rhGH on the Chinese market, launched in 1998 with the largest production capabilities and best quality in Asia.
Jintropin is the first the growth hormone brand in China which is purely 191 amino acid sequence and is therefore identical to the natural hGH, causing very little antibody formation in the body (around 2-3%). However the 192 amino acid hGH is different from the natural hGH, thus causing stronger antibodies formations in a majority of people.
Growth Hormone Deficiency
Found in both pediatric and adult patients, growth hormone deficiency (GHD) is a condition in which a person's body does not produce the amount of growth hormone necessary for normal bone and muscle growth. There are several causes for this condition; the most common being either mutated genes or a malformed pituitary gland. However, many cases of GHD are idiopathic, meaning that the cause of the deficiency is unknown.In children, GHD causes improper bone growth and muscle development...
Body Building Enhancement Drug
Human growth hormone has been used by body builders for years to promote physical enhancement. Human growth hormone raises your energy level and metabolism, causing you to both feel more active and burn fat. In fact, the only weight that you will gain while taking HGH is weight from lean muscle. Unlike steroids, the weight gain from HGH is slow - normal weight gain results are one to two pounds of lean muscle every two to three weeks...
Weight Loss Drug
HGH is a natural substance that is excreted by the pituitary glands in the human body. As a person ages, the level of HGH that their body produces decreases. However, human growth hormone drugs work to raise a person's levels of HGH back to a youth-like level, therefore aiding in weight loss. Human growth hormone works by increasing the amount of IGF-1 that a person's liver excretes. Normally, after you eat, your pancreas releases the amount of insulin necessary to transform carbohydrates into glucose...
* Pediatric growth hormone deficiency
* Severe burns
* Adult Growth hormone deficiency
User guide to Jintropin®:
- How to use
* Before administration, add 1ml of WFI to the rhGH vial of lyophilized powder, and make the solvent run slowly down
the side of the vial. Swirl the vial with a gentle rotary motion until contents are dissolved completely. Do not shake vigorously.
* The dose of administration should be individual for each patient. For growth-promotion purpose in children, the
recommended dose is 0.1-0.15 IU/kg/day, once per day, subcutaneous injection. The period of treatment is from 3 months to 3 years. Or follow your physicians prescription.
* For severe burn patients, a daily dose of 0.2-0.4I U/kg subcutaneous injection is recommended. The period of
treatment is about 2 weeks.
* The dose might require adjustment individually for human GH replacement therapy. Pls follow your physicians
- 191AA hGH vs 192AA hGH
Natural hGH has 191 amino acid residues. hGH made by genetic engineering has two types: those with 191 amino acids and those with 192 amino acids. Jintropin® is the only 191AA hGH brand in China. Jintropin® is the only officially approved hGH in China that are produced by its patented secretion technology to make it purely 191 amino acid hGH. Most of other Chinese
brands, although claim to be 191 amino acid hGH, in fact are still containing small amount of 192 amino acid hGH in there because of the technology they use. (See published paper, The many faces of growth hormone, Summer 2005, Body of Science)
- What’s the advantage of 191 amino acid hGH?
It is raising much less antibodies. The 191 amino acid hGH proteins are identical to the natural hGH, therefore pure 191 hGH causing very little antibody formation in the body. However the 192 amino acid hGH is different from the natural hGH,
thus causing stronger antibodies formations in a majority of people. These antibodies will make the hGH stop functioning.
- What's the advantage of Jintropin®'s secretion technology？
* Pure 191AA hGH
Jintropin® is the only hGH brand in China that are purely 191 amino acid. Because of this patented secretion technology.
Most other Chinese hGH brands, although claims there are also 191 amino acid hGH, are either 192 amino acid hGH or still
contain small amount of 192 amino acid by testing.
* The least amount of antibody formation caused
Jintropin® for injection causes the least amount of antibody formation (about 3%, like Genotropin® and Humatrope®) after one month injection (Jintropin® AQ doesn’t raise any at all). While most other Chinese brands typically cause antibody formation in about 25-50% of people. These antibodies will gradually stop your body’s hGH from functioning. Therefore always be
careful not to use a cheap, low quality brand of hGH.